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Cell Signaling Technology Inc
postsynaptic density protein 95 psd95 Postsynaptic Density Protein 95 Psd95, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more https://www.bioz.com/product/cst+cat+79777t/PSD95+XP+Rabbit+mAb/pmc12370956-163-49-54 Average 96 stars, based on 1 article reviews
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Image Search Results
Journal: Scientific Reports
Article Title: GDNF attenuates a-synuclein aggregation-induced damage to VTA-NAc dopaminergic transmission and alleviates depression-like behaviors in mice
doi: 10.1038/s41598-025-16556-7
Figure Lengend Snippet: Effect of AAV-SNCA on levels of DA, as well as the expression levels of protein in both the VTA and the NAc. ( A-D ) WB analysis of α-syn, p-α-syn, and TH in the VTA ( n = 5). ( E ) DA levels in the VTA and the NAc by ELISA ( n = 6; VTA: left Y axis, NAc: right Y axis). ( F-I ) WB analysis of SNAP-25, PSD95, and DAT in the NAc ( n = 5). ( J , K ) WB analysis of D1R and D2R in NAc ( n = 5). Data: Mean ± SEM; * P < 0.05, ** P < 0.01, *** P < 0.001 vs. AAV-NC1 (one-way ANOVA with Tukey’s test).
Article Snippet: The membranes were closed for 2 h at room temperature (20–25 °C) with 5% skimmed milk, which subsequently, were incubated overnight at 4 °C with specified primary antibodies (α-syn, Abcam, Cat# ab138501; TH, Santa, Cat# sc-374048; p-α-syn, Thermo Fisher Scientific, Cat# PA5-37740; synaptosomal-associated protein 25 (SNAP-25), Santa, Cat# sc-20038; postsynaptic density protein 95 (PSD95), CST, Cat# 3450 S; D2R, Santa, Cat# sc-5303; D1R, CST, Cat# #79777T;
Techniques: Expressing, Enzyme-linked Immunosorbent Assay
Journal: Scientific Reports
Article Title: GDNF attenuates a-synuclein aggregation-induced damage to VTA-NAc dopaminergic transmission and alleviates depression-like behaviors in mice
doi: 10.1038/s41598-025-16556-7
Figure Lengend Snippet: Effect of AAV-SNCA on levels of DA, as well as the expression levels of protein in both the VTA and the NAc. ( A-D ) WB analysis of α-syn, p-α-syn, and TH in the VTA ( n = 5). ( E ) DA levels in the VTA and the NAc by ELISA ( n = 6; VTA: left Y axis, NAc: right Y axis). ( F-I ) WB analysis of SNAP-25, PSD95, and DAT in the NAc ( n = 5). ( J , K ) WB analysis of D1R and D2R in NAc ( n = 5). Data: Mean ± SEM; * P < 0.05, ** P < 0.01, *** P < 0.001 vs. AAV-NC1 (one-way ANOVA with Tukey’s test).
Article Snippet: The membranes were closed for 2 h at room temperature (20–25 °C) with 5% skimmed milk, which subsequently, were incubated overnight at 4 °C with specified primary antibodies (α-syn, Abcam, Cat# ab138501; TH, Santa, Cat# sc-374048; p-α-syn, Thermo Fisher Scientific, Cat# PA5-37740; synaptosomal-associated protein 25 (SNAP-25), Santa, Cat# sc-20038; postsynaptic density protein 95 (PSD95), CST, Cat# 3450 S;
Techniques: Expressing, Enzyme-linked Immunosorbent Assay
Journal: Scientific Reports
Article Title: GDNF attenuates a-synuclein aggregation-induced damage to VTA-NAc dopaminergic transmission and alleviates depression-like behaviors in mice
doi: 10.1038/s41598-025-16556-7
Figure Lengend Snippet: The overexpression of GDNF counteracted the impact of α-syn aggregation on protein expression levels in both the VTA and NAc. ( A-D ) WB analysis of p-α-syn, GDNF and TH in the VTA ( n = 5). ( E-I ) WB analysis of SNAP-25, PSD95, D2R and D1R in the NAc ( n = 5). Data: Mean ± SEM; * P < 0.05, ** P < 0.01, *** P < 0.001 (one-way ANOVA with Tukey’s test).
Article Snippet: The membranes were closed for 2 h at room temperature (20–25 °C) with 5% skimmed milk, which subsequently, were incubated overnight at 4 °C with specified primary antibodies (α-syn, Abcam, Cat# ab138501; TH, Santa, Cat# sc-374048; p-α-syn, Thermo Fisher Scientific, Cat# PA5-37740; synaptosomal-associated protein 25 (SNAP-25), Santa, Cat# sc-20038; postsynaptic density protein 95 (PSD95), CST, Cat# 3450 S;
Techniques: Over Expression, Expressing
Journal: Scientific Reports
Article Title: GDNF attenuates a-synuclein aggregation-induced damage to VTA-NAc dopaminergic transmission and alleviates depression-like behaviors in mice
doi: 10.1038/s41598-025-16556-7
Figure Lengend Snippet: The overexpression of GDNF counteracted the impact of α-syn aggregation on protein expression levels in both the VTA and NAc. ( A-D ) WB analysis of p-α-syn, GDNF and TH in the VTA ( n = 5). ( E-I ) WB analysis of SNAP-25, PSD95, D2R and D1R in the NAc ( n = 5). Data: Mean ± SEM; * P < 0.05, ** P < 0.01, *** P < 0.001 (one-way ANOVA with Tukey’s test).
Article Snippet: The membranes were closed for 2 h at room temperature (20–25 °C) with 5% skimmed milk, which subsequently, were incubated overnight at 4 °C with specified primary antibodies (α-syn, Abcam, Cat# ab138501; TH, Santa, Cat# sc-374048; p-α-syn, Thermo Fisher Scientific, Cat# PA5-37740; synaptosomal-associated protein 25 (SNAP-25), Santa, Cat# sc-20038; postsynaptic density protein 95 (PSD95), CST, Cat# 3450 S; D2R, Santa, Cat# sc-5303; D1R, CST, Cat# #79777T; DAT, Santa, Cat# sc-32259;
Techniques: Over Expression, Expressing
Journal: Scientific Reports
Article Title: GDNF attenuates a-synuclein aggregation-induced damage to VTA-NAc dopaminergic transmission and alleviates depression-like behaviors in mice
doi: 10.1038/s41598-025-16556-7
Figure Lengend Snippet: Effect of AAV-SNCA on levels of DA, as well as the expression levels of protein in both the VTA and the NAc. ( A-D ) WB analysis of α-syn, p-α-syn, and TH in the VTA ( n = 5). ( E ) DA levels in the VTA and the NAc by ELISA ( n = 6; VTA: left Y axis, NAc: right Y axis). ( F-I ) WB analysis of SNAP-25, PSD95, and DAT in the NAc ( n = 5). ( J , K ) WB analysis of D1R and D2R in NAc ( n = 5). Data: Mean ± SEM; * P < 0.05, ** P < 0.01, *** P < 0.001 vs. AAV-NC1 (one-way ANOVA with Tukey’s test).
Article Snippet: The membranes were closed for 2 h at room temperature (20–25 °C) with 5% skimmed milk, which subsequently, were incubated overnight at 4 °C with specified primary antibodies (α-syn, Abcam, Cat# ab138501; TH, Santa, Cat# sc-374048; p-α-syn, Thermo Fisher Scientific, Cat# PA5-37740; synaptosomal-associated protein 25 (SNAP-25), Santa, Cat# sc-20038;
Techniques: Expressing, Enzyme-linked Immunosorbent Assay
Journal: Scientific Reports
Article Title: GDNF attenuates a-synuclein aggregation-induced damage to VTA-NAc dopaminergic transmission and alleviates depression-like behaviors in mice
doi: 10.1038/s41598-025-16556-7
Figure Lengend Snippet: The overexpression of GDNF counteracted the impact of α-syn aggregation on protein expression levels in both the VTA and NAc. ( A-D ) WB analysis of p-α-syn, GDNF and TH in the VTA ( n = 5). ( E-I ) WB analysis of SNAP-25, PSD95, D2R and D1R in the NAc ( n = 5). Data: Mean ± SEM; * P < 0.05, ** P < 0.01, *** P < 0.001 (one-way ANOVA with Tukey’s test).
Article Snippet: The membranes were closed for 2 h at room temperature (20–25 °C) with 5% skimmed milk, which subsequently, were incubated overnight at 4 °C with specified primary antibodies (α-syn, Abcam, Cat# ab138501; TH, Santa, Cat# sc-374048; p-α-syn, Thermo Fisher Scientific, Cat# PA5-37740; synaptosomal-associated protein 25 (SNAP-25), Santa, Cat# sc-20038;
Techniques: Over Expression, Expressing
Journal: Scientific Reports
Article Title: GDNF attenuates a-synuclein aggregation-induced damage to VTA-NAc dopaminergic transmission and alleviates depression-like behaviors in mice
doi: 10.1038/s41598-025-16556-7
Figure Lengend Snippet: Effect of AAV-SNCA on levels of DA, as well as the expression levels of protein in both the VTA and the NAc. ( A-D ) WB analysis of α-syn, p-α-syn, and TH in the VTA ( n = 5). ( E ) DA levels in the VTA and the NAc by ELISA ( n = 6; VTA: left Y axis, NAc: right Y axis). ( F-I ) WB analysis of SNAP-25, PSD95, and DAT in the NAc ( n = 5). ( J , K ) WB analysis of D1R and D2R in NAc ( n = 5). Data: Mean ± SEM; * P < 0.05, ** P < 0.01, *** P < 0.001 vs. AAV-NC1 (one-way ANOVA with Tukey’s test).
Article Snippet: The membranes were closed for 2 h at room temperature (20–25 °C) with 5% skimmed milk, which subsequently, were incubated overnight at 4 °C with specified primary antibodies (α-syn, Abcam, Cat# ab138501; TH, Santa, Cat# sc-374048; p-α-syn, Thermo Fisher Scientific, Cat# PA5-37740; synaptosomal-associated protein 25 (SNAP-25), Santa, Cat# sc-20038;
Techniques: Expressing, Enzyme-linked Immunosorbent Assay
Journal: Scientific Reports
Article Title: GDNF attenuates a-synuclein aggregation-induced damage to VTA-NAc dopaminergic transmission and alleviates depression-like behaviors in mice
doi: 10.1038/s41598-025-16556-7
Figure Lengend Snippet: The overexpression of GDNF counteracted the impact of α-syn aggregation on protein expression levels in both the VTA and NAc. ( A-D ) WB analysis of p-α-syn, GDNF and TH in the VTA ( n = 5). ( E-I ) WB analysis of SNAP-25, PSD95, D2R and D1R in the NAc ( n = 5). Data: Mean ± SEM; * P < 0.05, ** P < 0.01, *** P < 0.001 (one-way ANOVA with Tukey’s test).
Article Snippet: The membranes were closed for 2 h at room temperature (20–25 °C) with 5% skimmed milk, which subsequently, were incubated overnight at 4 °C with specified primary antibodies (α-syn, Abcam, Cat# ab138501; TH, Santa, Cat# sc-374048; p-α-syn, Thermo Fisher Scientific, Cat# PA5-37740; synaptosomal-associated protein 25 (SNAP-25), Santa, Cat# sc-20038;
Techniques: Over Expression, Expressing